H Conrad, William B Major, Michael A Cleary, Michele Ferrer, Marc Roberts, Brian Marine, Shane Chung, Namjin T Arthur, William J Chien, Andy D Berndt, Jason T Moon, Randall Data showing positive regulation of Wnt/β-catenin signal transduction by FAM129B siRNA using transcriptional reporter assay, target gene expression, and apoptosis assay <p>Data for Figure 2b. Measured β-catenin dependent firefly: constitutive renilla ratios for HT1080, A375, and A2058 reporter cells treated with the indicated conditions. Data for Figure 2c: Quantitative RT-PCR of β-catenin dependent Axin2 mRNA and housekeeping actin mRNA for HT1080, A375, and A2058 cells treated with the indicated conditions. Data for Figure 3a. Measured β-catenin dependent firefly: constitutive renilla ratios for A375 reporter cells treated with a dose curve of WNT3A or a single dose of WNT3A. Data for Figure 3b. Measured NFκB dependent firefly: constitutive renilla ratios for A375 reporter cells treated with a dose curve of TNFalpha or a single dose of TNFα . Data for Figure 4b. Quantitation of DAPI and TUNEL positive nuclei from A375 cells treated with WNT3A, PLX4720, and the control, FAM129B, or CTNNB1 siRNA.</p> melanoma;tumor;sirna;beta-catenin;fibrosarcoma cells;FAM129B;apopotosis;Medicine;Molecular Biology 2013-06-03
    https://f1000.figshare.com/articles/dataset/Data_showing_postive_regulation_of_Wnt_catenin_signal_transduction_and_Wnt_catenin_by_FAM129B_and_Wnt_dependent_transcriptional_reporter_regulation_by_FAM129B_siRNA/705153
10.6084/m9.figshare.705153.v1